Locoregional Management of In-Transit Metastasis in Melanoma

This is a clinical practice guideline for adult patients who were diagnosed with satellite lesions or in-transit metastases (ITM) from melanoma, with or without lymph node metastases. Available management options for these patients are discussed, such as the use of intralesional, topical, and regional therapies, and the recommended sequence of treatments is also addressed. Outcomes of interest include treatment response, disease recurrence, quality of life, toxicity, and survival.