Routine HPV Testing in Head and Neck Squamous Cell Carcinoma

This is a clinical practice guideline for adults with squamous cell carcinomas arising in the oropharynx, larynx, hypopharynx, nasopharynx, sinonasal tract, oral cavity subsites or an unknown primary head and neck site. The guideline examines routine testing for human papillomavirus (HPV) status in these patients, as well as the relationship between HPV positivity and cancer outcomes.