Primary Prophylaxis of Invasive Fungal Infections in Patients With Hematological Malignancies: 2017 Update of the Recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society for Hematology and Medical Oncology (DGHO)

This is a clinical practice guideline for adult patients with hematological malignancies, especially those receiving remission-induction therapy for acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). The guideline examines the primary prophylaxis of invasive fungal infections (IFI) in these patients using a variety of medications. Other topics discussed include newly developed targeted cancer therapies and their effects on risk of IFI, as well as the effects of therapeutic drug monitoring on the efficacy and safety of antifungal prophylaxis.