British Association of Dermatologists and British Photodermatology Group Guidelines for the Safe and Effective Use of Psoralen–Ultraviolet A Therapy 2015

This is a clinical practice guidelines on the use of psoralen-ultraviolet A (PUVA) photochemotherapy as a therapeutic modality for conditions including cutaneous T-cell lymphoma (CTCL). Topics of discussion that are specific to CTCL include a comparison between PUVA and other types of phototherapy such as narrowband ultraviolet B (TL-01) for treatment of patch-stage CTCL, as well as use of PUVA in early stage CTCL of the MF type. Adverse reactions are reviewed along with risk reduction measures and methods to manage treatment side-effects. Outcomes of interest for PUVA treatment of CTCL include response rates, remission duration, and survival.