The Role of Surgery in the Management of Patients with Diffuse Low Grade Glioma: A Systematic Review and Evidence-Based Clinical Practice Guideline

This is a clinical practice guideline for patients with diffuse low grade glioma (LGG). More specifically, these guideline recommendations apply to adults with imaging suggestive of a WHO grade 2 glioma (oligodendroglioma, astrocytoma, or oligo-astrocytoma). The central issue addressed in this guideline pertains to whether patients with imaging suggestive of LGG should undergo observation versus treatment involving a surgical procedure.