Recommendations for the Use of Long-term Central Venous Catheter (CVC) in Children with Hemato-oncological Disorders: Management of CVC-related Occlusion and CVC-related Thrombosis. On Behalf of the Coagulation Defects Working Group and the Supportive Therapy Working Group of the Italian Association of Pediatric Hematology and Oncology (AIEOP)

A clinical practice guideline for the use of long-term central venous catheters in pediatric hemato-oncological disorders. The guideline examines thrombosis prevention and secondary prophylaxis, and evaluation of removal. Outcomes of interest include reduced circulatory impairment, efficacy of treatment, and bleeding.