The purpose of this clinical practice guideline is to provide guidance to the primary oncology team so as to help ensure each patient within their care experiences the best quality of life possible throughout the illness trajectory. The guideline was developed to facilitate the appropriate integration of palliative care into oncology practice. The guideline outlines procedure for screening, assessment, palliative care interventions, reassessment, and after-death care. The panel initially focused on the needs of patients in their last 12 months of life. More recent versions, however, have expanded the focus to all patients and family experiencing cancer throughout the disease trajectory.