Guidelines for the Management of Mature T-cell and NK-cell Neoplasms (Excluding Cutaneous T-cell Lymphoma)

This is a clinical practice guideline for patients with mature T-cell and natural killer (NK)-cell neoplasms (excluding cutaneous T-cell lymphoma). Diagnostic assessment, staging, and treatment options are reviewed. The guideline also discusses antimicrobial prophylaxis and central nervous system (CNS) prophylaxis during therapy. Outcomes of interest include survival, response rate, rate of remission, disease progression, predictive value of diagnostic testing, and treatment related toxicity.