The Role of Liver Resection in Colorectal Cancer Metastases

This clinical practice guideline reviews surgical management of patients with liver metastases from colorectal cancer who have had or will have a complete resection of the primary cancer, and who meet the surgical criteria for the resection of liver-only metastases. The guideline examines the role of liver resection in special cases of liver plus extrahepatic metastases (EHM). The use of perioperative chemotherapy is also discussed. Outcomes of interest include median survival, three- and five-year survival, recurrence rate, postoperative complications, and chemotherapy-related hepatic injury.